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Copper‐Catalyzed Regioselective Synthesis of N ‐Aryl Amides from Aldoximes and Aryl Halides
Author(s) -
Panda Niranjan,
Mothkuri Raghavender,
Nayak Dinesh Kumar
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301868
Subject(s) - chemistry , regioselectivity , aryl , halide , catalysis , combinatorial chemistry , organic chemistry , ring (chemistry) , copper , medicinal chemistry , ligand (biochemistry) , alkyl , biochemistry , receptor
Abstract Ligand‐assisted copper‐catalyzed reaction of aldoximes with aryl halides is described for the regioselective synthesis of N ‐aryl amides. This protocol is simple and compatible with a wide range of functional groups attached to the aryl ring of the halides as well as aldoximes.