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Iron(III)‐Catalyzed Denitration Reaction: One‐Pot Three‐Component Synthesis of Imidazo[1,2‐ a ]pyridine Derivatives
Author(s) -
Yan Hao,
Wang Yuling,
Pan Congming,
Zhang Hao,
Yang Sizhuo,
Ren Xiaoyu,
Li Jian,
Huang Guosheng
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301658
Subject(s) - chemistry , pyridine , nitration , catalysis , component (thermodynamics) , medicinal chemistry , aminopyridines , organic chemistry , combinatorial chemistry , reaction conditions , coupling reaction , functional group , polymer , physics , thermodynamics
An iron(III)‐catalyzed one‐pot three‐component cross‐coupling nitration reaction of 2‐aminopyridines, aldehydes and nitroalkanes, straightforwardly forms imidazo[1,2‐ a ]pyridine derivatives and is described in this report. The system shows good functional‐group tolerance and proceeds smoothly in moderate to good yields.