Convenient Synthesis of Arylboronates through a Synergistic Pd/Cu‐Catalyzed Miyaura Borylation Reaction under Atmospheric Conditions | Zendy

Ratniyom Jadsada | Zendy; Dechnarong Nattanee | Zendy; Yotphan Sirilata | Zendy; Kiatisevi Supavadee | Zendy

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Convenient Synthesis of Arylboronates through a Synergistic Pd/Cu‐Catalyzed Miyaura Borylation Reaction under Atmospheric Conditions

Author(s) -

Ratniyom Jadsada,

Dechnarong Nattanee,

Yotphan Sirilata,

Kiatisevi Supavadee

Publication year - 2014

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201301634

Subject(s) - borylation , chemistry , catalysis , aryl , ligand (biochemistry) , combinatorial chemistry , medicinal chemistry , reaction conditions , organic chemistry , biochemistry , alkyl , receptor

A highly efficient and practical borylation reaction of aryl iodides with bis(pinacolato)diboron has been established. By using Pd(OAc) 2 , CuI, and PPh 3 as a ligand at room temperature under air in the presence of Cs 2 CO 3 , the protocol proved to be general. Various functionalized arylboronates were obtained in moderate to excellent yields. In addition, a possible reaction mechanism was proposed.

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