Premium
Short‐Step Anodic Access to Emissive RNA Homonucleosides
Author(s) -
Okada Yohei,
Shimada Kouhei,
Kitano Yoshikazu,
Chiba Kazuhiro
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301604
Subject(s) - chemistry , nucleobase , substituent , rna , glycoside , combinatorial chemistry , photochemistry , dna , stereochemistry , biochemistry , gene
Emissive RNA homonucleosides were added to the growing library of synthetic probes. The emissive nucleobases were constructed in one step from the methallyl C ‐glycoside of D ‐ribofuranose, which was prepared stereoselectively. The homonucleosides displayed various emission colors by using a single excitation wavelength that could be fine‐tuned merely by changing the carbonyl substituent on the methoxyphenol.