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Generation of Tetrahydro‐3 H ‐indeno[2,1‐ d ]pyrimidines by the Tandem Reaction of 2‐(2‐Alkynylphenyl)aziridines with 2‐Isocyanoacetates
Author(s) -
Zheng Danqing,
Wu Jie
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301426
Subject(s) - chemistry , trifluoromethanesulfonate , tandem , cascade reaction , copper , base (topology) , medicinal chemistry , reaction conditions , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , materials science , composite material , mathematical analysis , mathematics
A base‐promoted tandem reaction of 2‐(2‐alkynylphenyl)aziridines with 2‐isocyanoacetates in the presence of copper(II) triflate gives tetrahydro‐3 H ‐indeno[2,1‐ d ]pyrimidines in good yields, with the formation of two new rings and three bonds.