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Multicomponent Cascade Assembly for Quinolinopyranpyrazole Architectures
Author(s) -
Bakthadoss Manickam,
Devaraj Anthonisamy,
Kannan Damodharan
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301422
Subject(s) - chemistry , stereoselectivity , cascade , domino , cascade reaction , combinatorial chemistry , catalysis , column chromatography , solvent , organic chemistry , chromatography
A highly efficient, multicomponent protocol for the construction of functionalized quinolinopyranpyrazole scaffolds with high stereoselectivity has been developed through the application of a domino reaction. All the quinolinopyranpyrazoles were synthesized under solvent‐ and catalyst‐free conditions and required no work‐up or column chromatography.