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Copper‐Catalyzed N ‐ and O ‐Arylation of Amides: Alternative Approaches to 3,4‐Dihydroquinolin‐2‐ones, Quinolin‐2‐ones, and 12 H ‐Chromeno[2,3‐ b ]quinolin‐12‐ones
Author(s) -
Zhang Xinying,
Guo Xiaojie,
Fang Liangliang,
Song Yunping,
Fan Xuesen
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301373
Subject(s) - chemistry , copper , catalysis , combinatorial chemistry , organic chemistry , medicinal chemistry
The efficient syntheses of 3‐cyanoquinolin‐2‐ones, 3‐(2‐bromobenzyl)‐3‐cyano‐3,4‐dihydroquinolin‐2‐ones, 3‐(2‐bromobenzyl)quinolin‐2‐ones, and 12 H ‐chromeno[2,3‐ b ]quinolin‐12‐ones through copper‐catalyzed N ‐ and O ‐arylation of amides by using readily available 2‐bromobenzyl bromides and cyanoacetamides as starting materials were developed.