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ipso ‐Hydroxylation of Arylboronic Acids and Boronate Esters by Using Sodium Chlorite as an Oxidant in Water
Author(s) -
Gogoi Pranjal,
Bezboruah Pranjal,
Gogoi Junali,
Boruah Romesh C.
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301228
Subject(s) - chemistry , hydroxylation , phenols , sodium chlorite , organic chemistry , combinatorial chemistry , enzyme , chlorine dioxide
A facile and efficient procedure for the ipso ‐hydroxylation of arylboronic acids to phenols in water was developed. A series of electron‐rich and electron‐deficient arylboronic acids were smoothly ipso ‐hydroxylated with this protocol to afford products in excellent yields. Moreover, the protocol is amenable to boronate esters. In most cases, the phenolic products were obtained in pure form without any chromatographic purification.