Driving the Morita–Baylis–Hillman Reaction to a Multicomponent Organic Transformation | Zendy

Guillouzic AnneFrançoise | Zendy; Montel Sonia | Zendy; Laborde Coralie | Zendy; Volle JeanNoël | Zendy; Pirat JeanLuc | Zendy; Virieux David | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Driving the Morita–Baylis–Hillman Reaction to a Multicomponent Organic Transformation

Author(s) -

Guillouzic AnneFrançoise,

Montel Sonia,

Laborde Coralie,

Volle JeanNoël,

Pirat JeanLuc,

Virieux David

Publication year - 2014

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201301226

Subject(s) - chemistry , reagent , aldehyde , phosphine , lewis acids and bases , baylis–hillman reaction , olefin fiber , transformation (genetics) , organic chemistry , organic synthesis , organocatalysis , michael reaction , base (topology) , organic molecules , combinatorial chemistry , molecule , catalysis , enantioselective synthesis , biochemistry , gene , mathematical analysis , mathematics

The combination of a trivalent phosphorus reagent with an aldehyde and a Michael olefin in the presence of water led to the formation of functionalized phosphine oxides. This approach turned the Lewis base organocatalyzed Morita–Baylis–Hillman reaction into a multicomponent organic transformation to provide rapid access to polyfunctionalized molecules.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research