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Highly Enantioselective Alkylation of Allyl Acetates Using Tartrate‐Derived Bioxazoline Ligands
Author(s) -
Jayakumar Samydurai,
Prakash Muthuraj,
Balaraman Kaluvu,
Kesavan Venkitasamy
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301208
Subject(s) - chemistry , tsuji–trost reaction , enantioselective synthesis , tartrate , alkylation , chelation , allylic rearrangement , ring (chemistry) , medicinal chemistry , organic chemistry , stereochemistry , catalysis
Abstract Tartrate‐derived bioxazoline ligands, which form a five‐membered chelate ring with metals, were evaluated for use in the asymmetric allylic alkylation (AAA) reactions of various symmetrical and unsymmetrical allyl acetates. Excellent enantioselectivities were achieved by using both symmetrical and unsymmetrical allyl acetates.