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Iridium Catalysts with Chiral Bicyclic Pyridine–Phosphane Ligands for the Asymmetric Hydrogenation of Olefins
Author(s) -
Quan Xu,
Parihar Vijay Singh,
Bera Milan,
Andersson Pher G.
Publication year - 2014
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201301141
Subject(s) - chemistry , iridium , bicyclic molecule , pyridine , catalysis , asymmetric hydrogenation , reactivity (psychology) , enantioselective synthesis , noyori asymmetric hydrogenation , organic chemistry , medicinal chemistry , combinatorial chemistry , medicine , alternative medicine , pathology
New bicyclic pyridine–phosphane ligands were prepared, and their iridium complexes were evaluated in asymmetric hydrogenation of trisubstituted olefins with non‐coordinating and weakly coordinating substituents. The iridium catalysts showed high reactivity and enantioselectivity for both types of olefins.