Photoactivable Nonsymmetrical Bifunctional Linkers for Protein Immobilization on Attenuated Total Reflectance FTIR Optical Devices | Zendy

Hammaecher Catherine | Zendy; Joris Bernard | Zendy; Goormaghtigh Erik | Zendy; MarchandBrynaert Jacqueline | Zendy

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Photoactivable Nonsymmetrical Bifunctional Linkers for Protein Immobilization on Attenuated Total Reflectance FTIR Optical Devices

Author(s) -

Hammaecher Catherine,

Joris Bernard,

Goormaghtigh Erik,

MarchandBrynaert Jacqueline

Publication year - 2013

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201300939

Subject(s) - bifunctional , attenuated total reflection , chemistry , fourier transform infrared spectroscopy , maleimide , linker , infrared spectroscopy , polymer chemistry , organic chemistry , chemical engineering , catalysis , computer science , engineering , operating system

The photosensitive 4‐azido‐2,3,5,6‐tetrafluoro‐1‐benzoyl core has been connected to maleimide‐, chloroacetyloxy‐, or succinimidyl carbonate motifs through various spacers to furnish a series of bifunctional linkers. One linker ( 7a ) has been used for the construction of a biosensor for β‐lactam antibiotic detection by attenuated total reflectance FTIR (ATR‐FTIR) spectroscopy.

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