An Approach to 2,4‐Substituted Pyrazolo[1,5‐ a ]pyridines and Pyrazolo[1,5‐ a ]azepines by Ring‐Closing Metathesis | Zendy

Fustero Santos | Zendy; Román Raquel | Zendy; Asensio Amparo | Zendy; Maestro Miguel A. | Zendy; Aceña José L. | Zendy; SimónFuentes Antonio | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

An Approach to 2,4‐Substituted Pyrazolo[1,5‐ a ]pyridines and Pyrazolo[1,5‐ a ]azepines by Ring‐Closing Metathesis

Author(s) -

Fustero Santos,

Román Raquel,

Asensio Amparo,

Maestro Miguel A.,

Aceña José L.,

SimónFuentes Antonio

Publication year - 2013

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201300901

Subject(s) - azepine , chemistry , ring closing metathesis , peptidomimetic , metathesis , bicyclic molecule , stereochemistry , pyridine , ring (chemistry) , closing (real estate) , combinatorial chemistry , medicinal chemistry , organic chemistry , polymer , political science , law , peptide , biochemistry , polymerization

The ring‐closing metathesis (RCM) reactions of dienylpyrazoles have been employed in the synthesis of pyrazolo[1,5‐ a ]pyridine and pyrazolo[1,5‐ a ]azepine derivatives. Based on this approach, the diastereoselective synthesis of potential peptidomimetics containing four amino acid residues with the second ( i +1) and third ( i +2) fragments having been substituted by bicyclic frameworks is described.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research