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Gold‐Catalyzed Cascade Oxidative Cyclization and Arylation of Allenoates
Author(s) -
Zhang Rui,
Xu Qin,
Chen Kai,
Gu Peng,
Shi Min
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201300896
Subject(s) - chemistry , catalysis , oxidative phosphorylation , adduct , cascade , combinatorial chemistry , redox , aryl , catalytic cycle , medicinal chemistry , organic chemistry , biochemistry , alkyl , chromatography
An Au I /Au III catalytic system was found to be effective for the cascade oxidative arylation and cyclization of allenoates with arylboronic acids to give the corresponding cyclic adducts in moderate yields. This reaction system constitutes a new method for the synthesis of β‐aryl‐γ‐butenolides under mild conditions. Based on the previous mechanistic studies, a proposed Au I /Au III redox catalytic cycle has been outlined.