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Selectfluor‐Mediated Fluorination and C–C Bond Cleavage of Cyclohexene‐Fused Isoxazoline N ‐Oxides
Author(s) -
R.R. Rajawinslin,
Raihan Mustafa J.,
Janreddy Donala,
Kavala Veerababurao,
Kuo ChunWei,
Kuo TingShen,
Chen MeiLing,
He ChiuHui,
Yao ChingFa
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201300599
Subject(s) - selectfluor , chemistry , bond cleavage , cleavage (geology) , cyclohexene , organic chemistry , medicinal chemistry , catalysis , geotechnical engineering , fracture (geology) , engineering
A rapid method for the synthesis of long‐chain fluorinated compounds using a C–C bond‐cleavage reaction was developed. Selectfluor was the most effective fluorinating agent of those tested in this study. Long‐chain fluoro dioxo nitriles were formed from isoxazoline N ‐oxides via nitroso intermediates.