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Catalytic Enantioconvergent Decarboxylative Allylic Alkylation of Allyl Indolenin‐3‐carboxylates
Author(s) -
Kaiser Thomas M.,
Yang Jiong
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201300515
Subject(s) - chemistry , tsuji–trost reaction , allylic rearrangement , enantioselective synthesis , alkylation , catalysis , organic chemistry , quaternary carbon
A catalytic enantioconvergent process has been developed for the conversion of racemic allyl indolenin‐3‐carboxylates into enantiomerically enriched C3‐quaternary indolenines. A Pd‐catalyzed decarboxylative allylic alkylation reaction was employed for both stereoablation of the racemic allyl indolenin‐3‐carboxylates and enantioselective formation of the quaternary carbon center.