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Facile Synthesis of Functional Tricyclic Fused Furans by Intramolecular Wittig Reactions
Author(s) -
Tsai YiLing,
Das Utpal,
Syu Siangen,
Lee ChiaJui,
Lin Wenwei
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201300426
Subject(s) - wittig reaction , chemistry , intramolecular force , tricyclic , ylide , michael reaction , combinatorial chemistry , organic chemistry , substrate (aquarium) , catalysis , oceanography , geology
A convenient protocol for the preparation of tricyclic fused furans in one step starting from acid chlorides and Michael acceptors is described. The reaction conditions are mild, operationally simple, and have a broad substrate scope. The reaction is believed to proceed by an intramolecular Wittig reaction with a phosphorus ylide as the key intermediate.