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Stereoselective Synthesis of Tetrahydroquinolines Through an Imino‐Ene Cyclization Reaction
Author(s) -
Bondalapati Somasekhar,
Indukuri Kiran,
Ghosh Priya,
Saikia Anil K.
Publication year - 2013
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201201363
Subject(s) - chemistry , stereoselectivity , allylic rearrangement , ene reaction , diethyl ether , organic chemistry , ether , boron trifluoride , catalysis
Tetrahydroquinolines have been efficiently synthesized in good yields with excellent stereoselectivity. The reaction between α‐allylic anilines and aldehydes proceeds through an imino‐ene cyclization that is mediated by boron trifluoride–diethyl ether.