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One‐Pot Catalyst‐Free Synthesis of β‐ and γ‐Hydroxy Sulfides Using Diaryliodonium Salts and Microwave Irradiation
Author(s) -
Vaddula Buchi Reddy,
Varma Rajender S.,
Leazer John
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201201313
Subject(s) - chemistry , ethylene glycol , microwave irradiation , catalysis , potassium thiocyanate , thiocyanate , solvent , organic chemistry , base (topology) , combinatorial chemistry , mathematical analysis , mathematics
A simple and rapid one‐pot protocol is described for the preparation of α‐ and β‐hydroxy sulfides. The direct solvent‐free microwave irradiation of diaryliodonium salts, potassium thiocyanate, and ethylene glycol/β‐propylene glycol without any catalyst or base affords the final compounds in good yields (65–95 %) in around 10–25 min.