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Modular Synthesis of Planar‐Chiral para ‐Substituted Paracyclophanes by Double Suzuki Coupling
Author(s) -
Cakici Murat,
Bräse Stefan
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201201043
Subject(s) - chemistry , suzuki reaction , enantioselective synthesis , stereochemistry , molecule , coupling (piping) , modular design , planar chirality , planar , combinatorial chemistry , organic chemistry , catalysis , palladium , mechanical engineering , computer graphics (images) , computer science , engineering , operating system
The first synthesis of enantiomerically pure 4,7‐paracyclophane ditriflate starting from a quinone was reported. Using this molecule, mono‐ or dicoupling with boronic acids delivered enantiomerically pure arylparacyclophanes.