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Tandem Aldol Condensation/Platinacycle‐Catalyzed Addition Reactions of Aldehydes, Methyl Ketones, and Arylboronic Acids
Author(s) -
Liao YuanXi,
Hu QiaoSheng
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201200867
Subject(s) - chemistry , tandem , aldol condensation , aldol reaction , catalysis , organic chemistry , aldehyde , condensation , addition reaction , materials science , physics , composite material , thermodynamics
Aldol condensation of aldehydes with methyl ketones followed by anionic four‐electron donor‐based (type I) platinacycle‐catalyzed addition reactions of arylboronic acids to form β‐arylated ketones is described. Good to excellent yields of β‐arylated ketones were obtained for the tandem reactions of aromatic/aliphatic aldehydes, methyl ketones, and arylboronic acids, and moderate yields were observed for the tandem reactions of α,β‐unsaturated aldehydes.