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Preparation and Reactions of Aliphatic 2‐Pentafluorosulfanyl Aldehydes
Author(s) -
Ngo Silvana C.,
Lin JinHong,
Savoie Paul R.,
Hines Erica M.,
Pugliese Kaitlin M.,
Welch John T.
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201200763
Subject(s) - chemistry , organic chemistry , reaction conditions , aldehyde , combinatorial chemistry , catalysis
A facile preparation of aliphatic 2‐pentafluorosulfanyl aldehydes is described. To investigate the utility of the aldehydes as synthetic building blocks, various transformations of the aldehydes were explored. The pentafluorosulfanyl group was stable under a variety of reaction conditions, and the pentafluorosulfanylated products were obtained in moderate to good yields in most cases.