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Total Synthesis of Gabosines
Author(s) -
Mac Dinh Hung,
Chandrasekhar Srivari,
Grée René
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201200477
Subject(s) - chemistry , cyclohexanone , cyclohexenone , total synthesis , ring (chemistry) , organic chemistry , stereochemistry , catalysis
This review reports on the total synthesis of gabosines, a family of secondary metabolites containing trihydroxylated cyclohexanone or cyclohexenone cores. Analysis of the different stategies used to prepare these natural products and their stereoisomers has been carried out with special attention paid to the methods employed for the formation of the carbocyclic ring. The different methods are compared in a table, and a discussion of future directions of research in this area is presented.