A Three‐Component Condensation for the Construction of the Spiro[indoline‐3,3′‐piperidin]‐2‐one Skeleton | Zendy

Yang HaiBin | Zendy; Guan XiaoYang | Zendy; Wei Yin | Zendy; Shi Min | Zendy

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A Three‐Component Condensation for the Construction of the Spiro[indoline‐3,3′‐piperidin]‐2‐one Skeleton

Author(s) -

Yang HaiBin,

Guan XiaoYang,

Wei Yin,

Shi Min

Publication year - 2012

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201200185

Subject(s) - indoline , chemistry , dimethyl acetylenedicarboxylate , component (thermodynamics) , pyridine , condensation , skeleton (computer programming) , acetylenedicarboxylate , organic chemistry , medicinal chemistry , cycloaddition , catalysis , thermodynamics , physics , computer science , programming language

Treatment of pyridine and dimethyl acetylenedicarboxylate derivatives with N ‐substituted isatylidene derivatives resulted in three‐component condensations, affording 1′,9a′‐dihydrospiro[indoline‐3,2‐quinolizin]‐2‐one derivatives in high yields and with good diastereoselectivities through 1,4‐dipolar cycloadditions.

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