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Synthesis of Substituted Furans through Domino Aldol/Homo‐Michael Reactions of Formylcyclopropane 1,1‐Diesters with 1,3‐Dicarbonyls
Author(s) -
Bao Jilai,
Ren Jun,
Wang Zhongwen
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201200162
Subject(s) - aldol reaction , domino , chemistry , michael reaction , lewis acids and bases , lewis acid catalysis , cascade reaction , organic chemistry , combinatorial chemistry , catalysis
A Lewis acid catalyzed domino aldol/homo‐Michael reaction of formylcyclopropane 1,1‐diesters with dicarbonyls has been successfully developed. This method provides efficient and direct construction of highly functionalized furans from easily available starting materials.