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Facile Diastereoselective Entry to 4β‐Acylamidation of Neu5Ac2en Glycals Using Their N ‐Perfluoroacylated Congeners as Key Tools
Author(s) -
Rota Paola,
Agnolin Irene S.,
Allevi Pietro,
Anastasia Mario
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201200151
Subject(s) - chemistry , key (lock) , combinatorial chemistry , stereochemistry , organic chemistry , ecology , biology
Abstract An efficient protocol for the 4β‐acylamidation of the N ‐acylated glycals of Neu5Ac by using the corresponding N ‐perfluoroacylated congeners as key tools has been developed and applied to the synthesis of glycals combining the features of the molecules with antiviral properties.