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Dynamic Kinetic Resolution of β‐Amino Esters by a Heterogeneous System of a Palladium Nanocatalyst and Candida antarctica Lipase A (Eur. J. Org. Chem. 10/2011)
Author(s) -
Engström Karin,
Shakeri Mozaffar,
Bäckvall JanE.
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201190021
Subject(s) - candida antarctica , kinetic resolution , chemistry , racemization , lipase , palladium , amino acid , enantioselective synthesis , antifungal , organic chemistry , resolution (logic) , catalysis , enzyme , stereochemistry , biochemistry , medicine , dermatology , artificial intelligence , computer science
The cover picture shows the dynamic kinetic resolution of β‐amino esters, where racemization catalyzed by palladium nanoparticles is combined with enantioselective resolution by Candida antarctica lipase A (CALA). β‐Amino acids and esters are essential components of many biologically active compounds. Natural products containing β‐amino acids and esters have been found to hold many interesting properties, including insecticidal, antifungal and antitumor activity. Details are discussed in the Short Communication by J.‐E. Bäckvall et al. on p. 1827 ff. Background photo by Sixten Engström.

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