Premium
Synthesis of Paullone and Kenpaullone Derivatives by Photocyclization of 2‐(2‐Chloro‐1 H ‐indol‐3‐yl)‐ N ‐arylacetamides
Author(s) -
Li Zhanshan,
Lu Nianhong,
Wang Lihong,
Zhang Wei
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201101508
Subject(s) - chemistry , acetone , indole test , medicinal chemistry , organic chemistry , stereochemistry
An efficient synthesis of paullone and kenpaullone derivatives in moderate to high yields has been achieved through photocyclizations of (2‐chloro‐1 H ‐indole‐3‐yl)‐ N ‐arylacetamides in acetone at room temperature. Paullone and kenpaullone have been obtained easily and in high yields by deprotection of the photocyclization products.