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Concise Total Synthesis of Permethylated Anigopreissin A, a New Benzofuryl Resveratrol Dimer
Author(s) -
Chiummiento Lucia,
Funicello Maria,
Lopardo Maria Teresa,
Lupattelli Paolo,
Choppin Sabine,
Colobert Françoise
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201101422
Subject(s) - chemistry , sonogashira coupling , moiety , wittig reaction , total synthesis , dimer , furan , stereochemistry , resveratrol , combinatorial chemistry , organic chemistry , palladium , catalysis , biochemistry
The versatile preparation of permethylated anigopreissin A ( 1 ) has been accomplished from methyl 3,5‐dihydroxybenzoate. The key steps of the synthesis are sequential Sonogashira and Suzuki cross‐couplings for the construction of the 2,3‐diarylbenzo[ b ]furan moiety and Wittig olefination for the introduction of the styryl group.

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