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Synthesis of Fluorinated and Non‐Fluorinated Bicyclic Amidines through Ring‐Closing Metathesis
Author(s) -
Cuñat Ana C.,
Flores Sonia,
Oliver Judit,
Fustero Santos
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201101091
Subject(s) - bicyclic molecule , chemistry , metathesis , ring closing metathesis , fluorine , salt metathesis reaction , closing (real estate) , ring (chemistry) , combinatorial chemistry , stereochemistry , organic chemistry , political science , law , polymerization , polymer
An efficient method for the synthesis of fluorinated and non‐fluorinated imidazoazepines by a ring‐closing metathesis reaction as the key step is described. The influence of the fluorine atoms on the preparation of these bicyclic systems is also studied.