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First Acid‐Catalyzed Entry to O ‐Alkylated Hydroximides from Benzylic Alcohols
Author(s) -
Reddy Chada Raji,
Radhika Laghuvarapu,
Kumar Togapur Pavan,
Chandrasekhar Srivari
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201100797
Subject(s) - alkylation , chemistry , catalysis , organic chemistry , combinatorial chemistry
Abstract A facile method for the synthesis of O ‐alkylated hydroximides through the acid‐catalyzed alkylation of hydroximides by using benzylic alcohols as alkylating agents is described for the first time. The obtained O ‐propargylated products offered easy access to 2,5‐ and 4,5‐dihydroisoxazoles.