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Carboxylate‐Based, Room‐Temperature Ionic Liquids as Efficient Media for Palladium‐Catalyzed Homocoupling and Sonogashira–Hagihara Reactions of Aryl Halides
Author(s) -
Iranpoor Nasser,
Firouzabadi Habib,
Ahmadi Yasaman
Publication year - 2012
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201100701
Subject(s) - chemistry , sonogashira coupling , aryl , palladium , halide , ionic liquid , ligand (biochemistry) , catalysis , carboxylate , copper , combinatorial chemistry , coupling reaction , organic chemistry , biochemistry , alkyl , receptor
Carboxylate‐based salts are introduced as easily prepared, cheap and stable ionic liquids (ILs) that act as the base, ligand, reducing agent and media for the efficient phosphane‐free, palladium‐catalyzed homocoupling reaction of aryl iodides and bromides. The efficient copper and phosphane‐free Sonagashira coupling reaction of aryl iodides and bromides is also demonstrated in these ILs. One of the ILs was also phosphorylated and showed high efficiency and recyclability as a medium, and was also used as a ligand for palladium‐catalyzed homocoupling and copper‐free Sonogashira reactions of aryl iodides and bromides.