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A Novel Radical Cyclization Approach to Thieno‐Fused Heterocycles
Author(s) -
Singh Prabal P.,
Yadav Ashok K.,
Ila Hiriyakkanavar,
Junjappa Hiriyakkanavar
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201100516
Subject(s) - chemistry , radical cyclization , combinatorial chemistry , organic chemistry , stereochemistry
An efficient synthesis of novel aryl/heteroaryl‐substituted thieno‐fused heterocycles, that is, thieno[2,3‐ b ]thiophenes, thieno[2,3‐ b ]indoles, and pyrazolo[3,2‐ c ]thiophenes, involving radical‐mediated cyclization of 2‐(2‐bromoheteroaryl)‐3‐methylthio‐3‐aryl/heteroaryl acrylonitriles has been reported.
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