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Enyne‐Metathesis‐Based Tandem Processes
Author(s) -
Li Jingwei,
Lee Daesung
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201100438
Subject(s) - enyne metathesis , enyne , metathesis , chemistry , tandem , alkene , salt metathesis reaction , alkyne , acyclic diene metathesis , combinatorial chemistry , organic chemistry , catalysis , polymerization , materials science , composite material , polymer
Enyne metathesis is a powerful synthetic tool for generating 1,3‐dienes by redistributing unsaturated functionalities between an alkene and an alkyne via vinylalkylidene intermediates. Although less explored, enyne metathesis has a unique capacity for forming multiple C=C bonds and polycyclic systems in a tandem fashion. By exploiting these characteristics, various tandem reactions have been developed and applied to the synthesis of natural and unnatural products. This microreview recapitulates the recent advances in enyne‐metathesis‐based tandem processes under two main categories: Enyne metathesis/metathesis and enyne metathesis/nonmetathesis.