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Graphical Abstract: Eur. J. Org. Chem. 6/2010
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201090012
Subject(s) - racemization , chemistry , kinetic resolution , enantiomer , acylation , catalysis , organic chemistry , stereochemistry , enantioselective synthesis , combinatorial chemistry
The cover picture shows the synthesis of optically active esters and amides by chemoenzymatic dynamic kinetic resolution (DKR) from racemic alcohols and amines, respectively. Racemic substrates are transformed into single enantiomeric products by the combination of metal‐catalyzed racemization and enzymatic acylation. The background is “The Hands of Win‐Win” of Homigot, 22 km east of Pohang along the East Sea of Korea. Many people visit Homigot to see the hands and the sun rise. The hands are chiral and racemic. The Microreview by M.‐J. Kim, J. Park et al. on p. 999 ff describes the DKR of racemic alcohols and amines by emphasizing the characteristics of the racemization catalysts developed so far.