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Homocoupling of Terminal Alkynes Catalysed by Ultrafine Copper Nanoparticles on Titania
Author(s) -
Alonso Francisco,
Melkonian Taki,
Moglie Yanina,
Yus Miguel
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201001735
Subject(s) - chemistry , copper , catalysis , inert gas , piperidine , tetrahydrofuran , nanoparticle , solvent , inert , alkyne , base (topology) , organic chemistry , combinatorial chemistry , inorganic chemistry , polymer chemistry , nanotechnology , materials science , mathematical analysis , mathematics
Abstract Copper nanoparticles on titania effectively catalyse the oxidative homocoupling of terminal alkynes in the presence of piperidine as a base in tetrahydrofuran (THF) or under solvent‐free conditions. A wide range of diynes have been synthesised in high yields using low catalyst loading (1 mol‐% Cu). The copper catalyst (mainly as Cu 2 O) has been characterised by different means, is easy to prepare, can be reutilised several times, works either in air or under inert atmosphere and was shown to be superior to other commercially available copper sources.