Premium
Ring‐Opening of Epoxides in Water
Author(s) -
Bonollo Simona,
Lanari Daniela,
Vaccaro Luigi
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201001693
Subject(s) - chemistry , nucleophile , reactivity (psychology) , ring (chemistry) , organic chemistry , epoxide , green chemistry , reaction mechanism , catalysis , medicine , alternative medicine , pathology
Epoxides and water mix well together. The use of water represents an intriguing alternative to organic solvents, not only for developing green processes but also for exploring a totally new and peculiar reactivity. Epoxides react very efficiently in water with several nucleophiles, and several examples in the literature report that the use of water as reaction medium is essential for realizing processes that cannot be performed alternatively in other reaction media. This contribution is devoted to highlight the unique role of water in the ring‐opening reactions of epoxides.