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Acid‐Catalyzed [3,3] Sigmatropic Rearrangement of N ‐Cbz‐Diaryl Hydrazide for the Synthesis of Mono‐ N ‐Cbz‐1,1′‐biaryl‐2,2′‐diamine
Author(s) -
Suh SungEun,
Park InKeol,
Lim ByeongYun,
Cho CheonGyu
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201001461
Subject(s) - chemistry , hydrazide , sigmatropic reaction , diamine , catalysis , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry
Abstract N ‐Cbz‐Diaryl hydrazides undergo acid‐catalyzed [3,3] sigmatropic rearrangement to afford N ‐Cbz‐1,1′‐biaryl‐2,2′‐diamines. The resultant products can be versatile synthetic platforms for a wide variety of C 2 ‐ and/or nonsymmetric axially chiral ligands and organocatalysts.