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One‐Pot Atom‐Economic Synthesis of Thioselenophosphinates via a New Multicomponent Reaction of Secondary Phosphanes with Elemental Sulfur, Selenium, and Amines
Author(s) -
Artem'ev Alexander V.,
Gusarova Nina K.,
Malysheva Svetlana F.,
Mamatyuk Victor I.,
Gatilov Yurii V.,
Ushakov Igor A.,
Trofimov Boris A.
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201001189
Subject(s) - chemistry , selenium , sulfur , primary (astronomy) , toluene , elemental analysis , atom (system on chip) , organic chemistry , one pot synthesis , ethanol , catalysis , medicinal chemistry , physics , astronomy , computer science , embedded system
The multicomponent reaction between secondary phosphanes R 2 PH (R = Ph, arylalkyl, hetarylalkyl), elemental sulfur, selenium, and primary, secondary, or tertiary amines to afford the corresponding mono‐, di‐, and trialkylammonium thioselenophosphinates has been discovered. The atom‐economic reaction proceeds under mild conditions (ethanol/toluene, 40–70 °C, 40 min) to give the target alkylammonium thioselenophosphinates in high yields (up to 94 %).
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