Premium
Radical Intramolecular Arylation of Pyridinium Salts: A Straightforward Entry to 7‐Hydroxypyrido[2,1‐ a ]isoquinolinylium Salts
Author(s) -
Castillo Rafael R.,
Burgos Carolina,
Vaquero Juan J.,
AlvarezBuilla Julio
Publication year - 2011
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201001071
Subject(s) - chemistry , pyridinium , intramolecular force , pyridinium compounds , medicinal chemistry , combinatorial chemistry , organic chemistry
The synthesis of 7‐hydroxypyrido[2,1‐ a ]isoquinolinylium salts can be achieved in moderate yields by intramolecular radical arylation of pyridinium salts obtained from substituted pyridines and o ‐bromophenacyl bromides.