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Marine Toxins with Spiroimine Rings: Total Synthesis of Pinnatoxin A
Author(s) -
Beaumont Stéphane,
Ilardi Elizabeth A.,
Tappin Nicholas D. C.,
Zakarian Armen
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000842
Subject(s) - chemistry , total synthesis , marine toxin , stereochemistry , toxin , biochemistry
This microreview provides a compilation of synthetic approaches and total syntheses of pinnatoxin A in a survey of the literature up to early 2010. Pinnatoxin A is the first discovered and representative member of a fascinating group of potent marine toxins that share a spiroimine subunit as a unifying structural element.
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