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Acid‐Catalyzed Cascade Reactions of Enaminones with Aldehydes: C–H Functionalization To Afford 1,4‐Dihydropyridines
Author(s) -
Yang Jingyu,
Wang Chengyu,
Xie Xin,
Li Hongfeng,
Li Yanzhong
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000607
Subject(s) - chemistry , cascade , catalysis , surface modification , intramolecular force , cascade reaction , combinatorial chemistry , reaction conditions , organic chemistry , chromatography
An efficient acid‐catalyzed approach to the synthesis of functional 1,4‐dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.
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