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Chan–Lam–Evans Coupling of Cbz‐Protected Histidines
Author(s) -
DalZotto Christophe,
Michaux Julien,
MartinandLurin Elodie,
Campagne JeanMarc
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000591
Subject(s) - chemistry , evans blue , yield (engineering) , surface modification , stereochemistry , combinatorial chemistry , medicine , materials science , metallurgy
Direct functionalization of protected histidines with arylboronic acids is described under Chan–Lam–Evans conditions to give the corresponding N (τ)‐arylhistidines in moderate to good yields (12 examples, up to 83 % yield) under mild conditions.
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