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Amberlyst‐15 in Ionic Liquid: An Efficient and Recyclable Reagent for Nucleophilic Substitution of Alcohols and Hydroamination of Alkenes
Author(s) -
Qureshi Ziyauddin S.,
Deshmukh Krishna M.,
Tambade Pawan J.,
Dhake Kishor P.,
Bhanage Bhalchandra M.
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000456
Subject(s) - chemistry , hydroamination , reagent , ionic liquid , tetrafluoroborate , nucleophilic substitution , organic chemistry , nucleophile , yield (engineering) , substitution reaction , solvent , combinatorial chemistry , catalysis , materials science , metallurgy
Abstract The nucleophilic substitution reaction of secondary alcohols and hydroamination of alkenes with amides, sulfonamides, carbamates, and amines using Amberlyst‐15 immobilized in [Bmim][BF 4 ] (1‐butyl‐3‐methylimidazolium tetrafluoroborate) ionic liquid as an efficient recyclable reagent is described. The solvent effect is prominent in the reaction, and the desired substitution products are obtained in good to excellent yield. The protocol is advantageous due to the ease of handling of the reagents, the simple work‐up procedure, and the environmentally benign conditions that allow effective recyclability.