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Addition/Cycloaddition of Acetylenedicarboxylates to Open‐Chain or Cyclic Amino Carbonyl Compounds
Author(s) -
Guerrini Giacomo,
Ponticelli Fabio
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000371
Subject(s) - chemistry , cycloaddition , pyrazolones , chain (unit) , reactivity (psychology) , molecule , organic chemistry , stereochemistry , combinatorial chemistry , catalysis , medicine , physics , alternative medicine , pathology , astronomy
Some new, interesting, and unknown heterocyclic rings and open‐chain molecules have been obtained with ease and under mild conditions by reaction of a wide range of aminocarbonyl compounds with acetylenic esters. The reactivity is highly dependent on the substituents and their positions in the starting material, which can be either cyclic (pyrazolones) or open‐chain compounds.