Metabolites from the Mangrove Endophytic Fungus  Phomopsis  sp. (#zsu‐H76) | Zendy

Yang Jianxiang | Zendy; Xu Fang | Zendy; Huang Caihuan | Zendy; Li Jing | Zendy; She Zhigang | Zendy; Pei Zhong | Zendy; Lin Yongcheng | Zendy

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Metabolites from the Mangrove Endophytic Fungus Phomopsis sp. (#zsu‐H76)

Author(s) -

Yang Jianxiang,

Xu Fang,

Huang Caihuan,

Li Jing,

She Zhigang,

Pei Zhong,

Lin Yongcheng

Publication year - 2010

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.201000329

Subject(s) - mangrove , chemistry , phomopsis , fungus , stereochemistry , plant use of endophytic fungi in defense , endophyte , botany , biology , ecology

Three unique metabolites, namely, phomopsis‐H76 A ( 1 ), B ( 2 ), and C ( 3 ), were isolated from the mangrove endophytic fungus Phomopsis sp. (#zsu‐H76). Structures were determined by spectroscopic methods, mainly 1D and 2D NMR spectroscopy. Compound 1 – 3 are all dimers. Compounds 2 and 3 possesses a pyrano[4,3‐ b ]pyran‐5(2 H )‐one ring system that is unprecedented in nature. Primary bioassays showed that 1 accelerated the growth of subintestinal vessel plexus (SIV) branch markedly, whereas 3 showed inhibition of SIV. Compounds 1 – 3 showed no activity in antibacterial and cytotoxic tests.

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