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Bis‐Carbaborane‐Bridged Bis‐Glycophosphonates as Boron‐Rich Delivery Agents for BNCT
Author(s) -
Stadlbauer Sven,
Lönnecke Peter,
Welzel Peter,
HeyHawkins Evamarie
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000213
Subject(s) - chemistry , boron , solubility , water soluble , combinatorial chemistry , organic chemistry
Abstract The synthesis and properties of boron‐rich bis( meta ‐carbaborane) derivatives containing glycophosphonate and glycophosphonothioate moieties are reported. All compounds are water‐soluble; however, the tetragalactosylated compounds show lower solubility than their disodium salts.