Premium
Synthesis of Symmetric Diester‐Functionalised Tröger's Base Analogues
Author(s) -
Bhuiyan M. Delower H.,
Zhu KaiXian,
Jensen Paul,
Try Andrew C.
Publication year - 2010
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201000086
Subject(s) - chemistry , aniline , base (topology) , ring (chemistry) , solubility , organic chemistry , stereochemistry , polymer chemistry , medicinal chemistry , mathematical analysis , mathematics
The yields of ester‐functionalised Tröger's base analogues are dramatically improved by incorporating an electron‐donating group on the aromatic ring and/or enhancing solubility of the aniline unit. In addition to 2,8‐diester compounds, 1,7‐, 3,9‐ and 4,10‐diester‐functionalised Tröger's base analogues have been prepared for the first time.