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Graphical Abstract: Eur. J. Org. Chem. 27/2009
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200990077
Subject(s) - chemistry , bifunctional , lewis acids and bases , aldol reaction , enamine , catalysis , stereoselectivity , cover (algebra) , ligand (biochemistry) , lewis acid catalysis , stereochemistry , organic chemistry , combinatorial chemistry , mechanical engineering , biochemistry , receptor , engineering
The cover picture shows aldol reactions catalyzed by an enamine–metal Lewis acid bifunctional catalyst. The proposed transition state is also shown at the top. This bifunctional catalyst was developed by using a tridentate ligand to bring the Lewis acid and Lewis base in close proximity without quenching each other. The catalyst was found to catalyze aldol reactions in high activity and stereoselectivity. Details are discussed in the Short Communication by H. Wong et al. on p. 4581 ff. The authors acknowledge Bo Wang for helping with the cover page design and Mike Novak for useful discussions.