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Graphical Abstract: Eur. J. Org. Chem. 22/2009
Publication year - 2009
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.200990062
Subject(s) - mutant , chemistry , fluorescence , cover (algebra) , biophysics , biochemistry , physics , biology , gene , optics , mechanical engineering , engineering
The cover picture shows the bioactivity for rescue of diapause in daf‐9(dh6) mutant worms using (25 S )‐Δ 7 ‐dafachronic acid (structure, bottom left). The fluorescence label (represented by purple spots) marks the daf‐9(dh6) ; dhEx24 mutant worms that develop into adults without the requirement of exogenous hormonally active steroidal acid. The daf‐9(dh6) mutant worms (no fluorescence, at the bottom) can develop into adults by using (25 S )‐Δ 7 ‐dafachronic acid at concentrations down to 10 n M (top right). Details are discussed in the article by H.‐J. Knölker et al. on p. 3703 ff.